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Cancer is the growth of abnormal cells that
invade and destroy other tissues and is classified according to
the tissue and the cell type of origin.
Melanoma
Cancer, or skin cancer, is characterized by a dark-pigmented, usually
malignant tumor arising from a melanocyte, an epidermal cell capable
of synthesizing melanin (pigment).
The Melanoma Cancer Animation aired on the Discover Health
Channel
and helped communicate the complexities of DNA treatment to millions
of viewers.
This vaccine utilizes DNA technology in order to equip the body's
own immune system to recognize and destroy tumor cells. This
process is very complex and requires a great deal of time to communicate
using conventional multimedia, such as regular PowerPoint®
slides narrated by a speaker.
We were able to animate the entire process in under two minutes.
The animation includes the process of how killer T cells will fail
to recognize a cancer cell without MHC class proteins expressed
on the cell surface.
This treatment is designed to target tumor cells by the insertion
of small, circular pieces of DNA, known as plasmids, that contain
the genes for the MHC class proteins. Once
injected, the tumor cells absorb the DNA and begin to make the MHC
class proteins. These proteins are then displayed on the surface
of the tumor cell which then alert killer T cells. The T cells can
then recognize the tumor cells as foreign and destroy them.
Advanced melanoma cancer that turns metastatic can be deadly. DNA
technology is able to target advanced melanoma cancer and is a much
better alternative then chemotherapy which uses toxic chemicals
that sometimes result in damage to other cells and organs.
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